Versatile Manufacturing Capacity

Ma’anshan c-GMP Manufacturing Site

GMP production line, up to multi-hundred-kilogram scale

>120 reactors, from 500 L to 5000 L

320,000 L total reactor capacity

APIs, Intermediates Manufacturing and Process Development

Ma’anshan HPAPI Manufacturing Site

4 GMP production lines, up to multi-kilogram scale

4000 L total reactor capacity

OEL <0.01 μgm-3

HPAPI & ADC Payload-Linkers, API and Intermediates Manufacturing and Process Development, Analytical Methods Research & Development

Chongqing ADC Manufacturing Site

Protein production: 200 L, 500 L or 2000 L scale

Bioconjugation line: 200 L scale

ADC Manufacturing and Process Development, Lyophilised Protein/ADC production, Drug Product Filling

Qidong GMP Drug Product Manufacturing Site

Oral Solid Dosage (OSD) manufacturing: ~1 billion per annum

Topical Semi-solid Dosage manufacturing: ~40 million tubes per annum

Formulation development and manufacturing for solid and semi-solid drug products: tablets, capsules, granules, powders, creams and gels.

Heze Manufacturing Site

Non-GMP production line, up to multi-hundred-kilogram scale

47 reactors, from 500 L to 5000 L

116,000 L total reactor capacity

Speciality chemicals and intermediates manufacturing.

Shanghai R&D Centre

Process Development & Manufacturing: Early-stage discovery, pre-clinical

APIs, Drug Conjugates, Protein Degraders, Building Blocks, Peptides, Oligonucleotides

Shanghai 2Y-Chem R&D Centre

GMP Kilo Lab

Chemistry, Materials & Controls Research & Development for APIs and Formulation.