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Precision Crosslinkers & Spacers for Bioconjugation

Hydrophilic, hydrophobic, flexible, rigid, cleavable or not – Fluorochem stock a range of linkers and spacers to fine-tune your bioconjugation strategies, ensuring optimal stability, functionality, and performance.

Browse Crosslinkers & Spacers

Browse Crosslinkers & Spacers

When linking biomolecules together, the nature of the link itself can’t be forgotten. Length, solubility, flexibility, cleavability, and the chemistry of attachment will have an impact on the properties of the bioconjugate. Either used alone, or in combination with further bioconjugation reagents, our array of crosslinkers and spacers can help fine-tune the properties of any bioconjugate.

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Home > Products > Bioconjugation > Crosslinkers & Spacers

Cleavable

Create bioconjugates that break down when you need them to. Fluorochem’s stock these essential ADC linkers, including photocleavable linkages.

Heterobifunctional

Selectively form specific bioconjugates – Fluorochem offer a wide choice of crosslinkers ideal for creating drug-conjugates or combining different biomolecules.

Homobifunctional

Rapidly crosslink biomolecules and form stable, stochastic conjugates. Our catalogue of linkers can crosslink everything from proteins to hydrogels.

PEGs

Find the right PEG you need with our selection of linkers, covering a wide range of functional groups and sizes.

8-Bromooctanoic acid

8-Bromooctanoic acid

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1,6-Dibromohexane

1,6-Dibromohexane

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1,5-Dibromopentane

1,5-Dibromopentane

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6-Bromohexanenitrile

6-Bromohexanenitrile

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1-Chloro-6-hydroxyhexane

1-Chloro-6-hydroxyhexane

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Undec-10-enyl bromide

Undec-10-enyl bromide

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1-Bromo-5-chloropentane

1-Bromo-5-chloropentane

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9-Decenoic acid

9-Decenoic acid

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Bis[2-(2-chloroethoxy)ethyl]ether

Bis[2-(2-chloroethoxy)ethyl]ether

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6-Bromohexaneamide

6-Bromohexaneamide

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6-Bromohexanoic acid

6-Bromohexanoic acid

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6-Bromohexanoyl chloride

6-Bromohexanoyl chloride

{"author_name":"[email protected]","post_title":"6-Bromohexanoyl chloride","has_stock":{"has_stock_uk":"true","has_stock_germany":"false","has_stock_china":"true","has_stock_any":"true"},"sds_links":{"EN":"https:\/\/sds.fluorochem.co.uk\/eng\/sds_F003076_en.pdf","DA":"https:\/\/sds.fluorochem.co.uk\/dan\/sds_F003076_da.pdf","NL":"https:\/\/sds.fluorochem.co.uk\/nld\/sds_F003076_nl.pdf","FI":"https:\/\/sds.fluorochem.co.uk\/fin\/sds_F003076_fi.pdf","FR":"https:\/\/sds.fluorochem.co.uk\/fra\/sds_F003076_fr.pdf","DE":"https:\/\/sds.fluorochem.co.uk\/deu\/sds_F003076_de.pdf","IT":"https:\/\/sds.fluorochem.co.uk\/ita\/sds_F003076_it.pdf","NO":"https:\/\/sds.fluorochem.co.uk\/nor\/sds_F003076_no.pdf","PT":"https:\/\/sds.fluorochem.co.uk\/por\/sds_F003076_pt.pdf","ES":"https:\/\/sds.fluorochem.co.uk\/spa\/sds_F003076_es.pdf","SV":"https:\/\/sds.fluorochem.co.uk\/swe\/sds_F003076_sv.pdf"},"min_max_price":{"min_gbp_base_price":14,"max_gbp_base_price":136},"transport":{"un_number":3265,"packing_group":"II","hazard_class":8,"hazard_subclass":"","shipping_name":"CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S."},"post_content":"CAS [22809-37-6]","hazards":{"signal_word":"Danger","hazard_statements":["EUH014 - Reacts violently with water.","H314 - Causes severe skin burns and eye damage.","H335 - May cause respiratory irritation."],"precautionary_phrases":["P223 - Do not allow contact with water.","P260 - Do not breathe dust\/fume\/gas\/mist\/vapours\/spray.","P264 - Wash hands thoroughly after handling.","P270 - Do not eat, drink or smoke when using this product.","P271 - Use only outdoors or in a well-ventilated area.","P280 - Wear protective gloves\/protective clothing and eye\/face protection.","P301+P310 - IF SWALLOWED: Immediately call a POISON CENTER\/doctor.","P301+P330+P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.","P302+P352 - IF ON SKIN: Wash with plenty of water and soap.","P303+P361+P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.","P304+P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing.","P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.","P308+P313 - IF exposed or concerned: Get medical advice\/attention.","P310 - Immediately call a POISON CENTER\/doctor.","P321 - Specific treatment (see Section 4 on this SDS).","P335 - Brush off loose particles from skin.","P362+P364 - Take off contaminated clothing and wash it before reuse.","P403+P233 - Store in a well-ventilated place. Keep container tightly closed.","P405 - Store locked up.","P501 - Dispose of contents\/container to hazardous waste disposal."],"ghs_pictograms":["GHS05","GHS07"]},"variants_blob_url":"https:\/\/fluorochemcouk.blob.core.windows.net\/pricing\/F003076.json","post_name":"6-bromohexanoyl-chloride","post_date":"2025-03-21T11:27:01+00:00","meta":{"_cas":"22809-37-6","_canonicalsmiles":"O=C(Cl)CCCCCBr","_inchi":"InChI=1S\/C6H10BrClO\/c7-5-3-1-2-4-6(8)9\/h1-5H2","_inchikey":"HBPVGJGBRWIVSX-UHFFFAOYSA-N","_mdl":"MFCD00000761","_einecs":"245-236-7","_molecularformula":"C6H10BrClO","_unspsc":12352100,"_sku":"F003076","_synonyms":["6-Bromocaproyl chloride","6-Bromohexanoic acid chloride"]},"shipping_times":{"UK":"UK Stock, Next Day, Germany Stock 3- 5 days, China Stock 10 - 14 days.","EU":"EU Stock, Next Day, UK Stock 3- 5 days, China Stock 10 - 14 days."},"post_type":"product","post_modified":"2025-06-25T08:51:03","ID":"769029","post_status":"publish","categories":{"concept_groups":["Acyl halide","Chlorinated","Brominated","Halogenated","Acyl chloride"],"term_id":[130,93]},"author_id":"1946","permalink":"https:\/\/fluorochem.build\/product\/F003076\/","properties":{"purity":"97.0%","molecular_weight":"213.5","state":"Liquid","flash_point":"110\u00b0C","boiling_range":"130\u00b0C at 20 mmHg","relative_density":"1.395","appearance":"Clear colourless liquid"}}

10-Bromo-1-decene

10-Bromo-1-decene

{"author_name":"[email protected]","post_title":"10-Bromo-1-decene","has_stock":{"has_stock_uk":"true","has_stock_germany":"true","has_stock_china":"true","has_stock_any":"true"},"sds_links":{"EN":"https:\/\/sds.fluorochem.co.uk\/eng\/sds_F003439_en.pdf","DA":"https:\/\/sds.fluorochem.co.uk\/dan\/sds_F003439_da.pdf","NL":"https:\/\/sds.fluorochem.co.uk\/nld\/sds_F003439_nl.pdf","FI":"https:\/\/sds.fluorochem.co.uk\/fin\/sds_F003439_fi.pdf","FR":"https:\/\/sds.fluorochem.co.uk\/fra\/sds_F003439_fr.pdf","DE":"https:\/\/sds.fluorochem.co.uk\/deu\/sds_F003439_de.pdf","IT":"https:\/\/sds.fluorochem.co.uk\/ita\/sds_F003439_it.pdf","NO":"https:\/\/sds.fluorochem.co.uk\/nor\/sds_F003439_no.pdf","PT":"https:\/\/sds.fluorochem.co.uk\/por\/sds_F003439_pt.pdf","ES":"https:\/\/sds.fluorochem.co.uk\/spa\/sds_F003439_es.pdf","SV":"https:\/\/sds.fluorochem.co.uk\/swe\/sds_F003439_sv.pdf"},"min_max_price":{"min_gbp_base_price":14,"max_gbp_base_price":802},"transport":[],"post_content":"CAS [62871-09-4]","hazards":{"signal_word":"Warning","hazard_statements":["H302 - Harmful if swallowed.","H315 - Causes skin irritation.","H319 - Causes serious eye irritation.","H335 - May cause respiratory irritation."],"precautionary_phrases":["P101 - If medical advice is needed, have product container or label at hand.","P260 - Do not breathe dust\/fume\/gas\/mist\/vapours\/spray.","P264 - Wash hands thoroughly after handling.","P270 - Do not eat, drink or smoke when using this product.","P271 - Use only outdoors or in a well-ventilated area.","P280 - Wear protective gloves\/protective clothing and eye\/face protection.","P301+P310 - IF SWALLOWED: Immediately call a POISON CENTER\/doctor.","P301+P330+P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.","P303+P361+P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.","P304+P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing.","P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.","P321 - Specific treatment (see Section 4 on this SDS).","P362+P364 - Take off contaminated clothing and wash it before reuse.","P403+P233 - Store in a well-ventilated place. Keep container tightly closed.","P405 - Store locked up.","P501 - Dispose of contents\/container to hazardous waste disposal."],"ghs_pictograms":["GHS07"]},"variants_blob_url":"https:\/\/fluorochemcouk.blob.core.windows.net\/pricing\/F003439.json","post_name":"10-bromo-1-decene","post_date":"2025-03-21T11:26:46+00:00","meta":{"_cas":"62871-09-4","_canonicalsmiles":"C=CCCCCCCCCBr","_inchi":"InChI=1S\/C10H19Br\/c1-2-3-4-5-6-7-8-9-10-11\/h2H,1,3-10H2","_inchikey":"JVVPJOMYWVYPOF-UHFFFAOYSA-N","_mdl":"MFCD00078660","_molecularformula":"C10H19Br","_unspsc":12352100,"_sku":"F003439","_synonyms":[]},"shipping_times":{"UK":"UK Stock, Next Day, Germany Stock 3- 5 days, China Stock 10 - 14 days.","EU":"EU Stock, Next Day, UK Stock 3- 5 days, China Stock 10 - 14 days."},"post_type":"product","post_modified":"2025-06-25T08:51:03","ID":"768391","post_status":"publish","categories":{"concept_groups":["Brominated","Halogenated","Alkene"],"term_id":[130,93]},"author_id":"1946","permalink":"https:\/\/fluorochem.build\/product\/F003439\/","properties":{"purity":"97.0%","molecular_weight":"219.166","state":"Liquid","flash_point":"97\u00b0C","boiling_range":"50\u00b0C","relative_density":"1.092","appearance":"Liquid"}}

5-Chloro-1-pentanol

5-Chloro-1-pentanol

{"author_name":"[email protected]","post_title":"5-Chloro-1-pentanol","has_stock":{"has_stock_uk":"true","has_stock_germany":"true","has_stock_china":"true","has_stock_any":"true"},"sds_links":{"EN":"https:\/\/sds.fluorochem.co.uk\/eng\/sds_F008844_en.pdf","DA":"https:\/\/sds.fluorochem.co.uk\/dan\/sds_F008844_da.pdf","NL":"https:\/\/sds.fluorochem.co.uk\/nld\/sds_F008844_nl.pdf","FI":"https:\/\/sds.fluorochem.co.uk\/fin\/sds_F008844_fi.pdf","FR":"https:\/\/sds.fluorochem.co.uk\/fra\/sds_F008844_fr.pdf","DE":"https:\/\/sds.fluorochem.co.uk\/deu\/sds_F008844_de.pdf","IT":"https:\/\/sds.fluorochem.co.uk\/ita\/sds_F008844_it.pdf","NO":"https:\/\/sds.fluorochem.co.uk\/nor\/sds_F008844_no.pdf","PT":"https:\/\/sds.fluorochem.co.uk\/por\/sds_F008844_pt.pdf","ES":"https:\/\/sds.fluorochem.co.uk\/spa\/sds_F008844_es.pdf","SV":"https:\/\/sds.fluorochem.co.uk\/swe\/sds_F008844_sv.pdf"},"min_max_price":{"min_gbp_base_price":7,"max_gbp_base_price":404},"cofa":{"cofa_batches":[{"batch":"FCC32384","link":"https:\/\/fluorochemcouk.blob.core.windows.net\/cofa\/F008844_FCC32384.pdf"}]},"transport":[],"post_content":"CAS [5259-98-3]","hazards":{"signal_word":"Warning","hazard_statements":["H302 - Harmful if swallowed.","H315 - Causes skin irritation.","H319 - Causes serious eye irritation.","H332 - Harmful if inhaled.","H335 - May cause respiratory irritation."],"precautionary_phrases":["P260 - Do not breathe dust\/fume\/gas\/mist\/vapours\/spray.","P264 - Wash hands thoroughly after handling.","P270 - Do not eat, drink or smoke when using this product.","P271 - Use only outdoors or in a well-ventilated area.","P280 - Wear protective gloves\/protective clothing and eye\/face protection.","P301+P310 - IF SWALLOWED: Immediately call a POISON CENTER\/doctor.","P301+P330+P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.","P302+P352 - IF ON SKIN: Wash with plenty of water and soap.","P303+P361+P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.","P304+P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing.","P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.","P308+P313 - IF exposed or concerned: Get medical advice\/attention.","P321 - Specific treatment (see Section 4 on this SDS).","P342+P311 - If experiencing respiratory symptoms: Call a POISON CENTER\/doctor.","P362+P364 - Take off contaminated clothing and wash it before reuse.","P403+P233 - Store in a well-ventilated place. Keep container tightly closed.","P405 - Store locked up.","P501 - Dispose of contents\/container to hazardous waste disposal."],"ghs_pictograms":["GHS07"]},"variants_blob_url":"https:\/\/fluorochemcouk.blob.core.windows.net\/pricing\/F008844.json","post_name":"5-chloro-1-pentanol","post_date":"2025-03-21T11:28:00+00:00","meta":{"_cas":"5259-98-3","_canonicalsmiles":"OCCCCCCl","_inchi":"InChI=1S\/C5H11ClO\/c6-4-2-1-3-5-7\/h7H,1-5H2","_inchikey":"DCBJCKDOZLTTDW-UHFFFAOYSA-N","_mdl":"MFCD00039556","_molecularformula":"C5H11ClO","_unspsc":12352100,"_sku":"F008844","_synonyms":[]},"shipping_times":{"UK":"UK Stock, Next Day, Germany Stock 3- 5 days, China Stock 10 - 14 days.","EU":"EU Stock, Next Day, UK Stock 3- 5 days, China Stock 10 - 14 days."},"post_type":"product","post_modified":"2025-06-25T08:51:04","ID":"771773","post_status":"publish","categories":{"concept_groups":["Aliphatic alcohol","Chlorinated","Halogenated"],"term_id":[130,93]},"author_id":"1946","permalink":"https:\/\/fluorochem.build\/product\/F008844\/","properties":{"purity":"90.0%","molecular_weight":"122.59","state":"Liquid","boiling_range":"107 to 108\u00b0C at 10 mmHg","relative_density":"1.06","appearance":"Clear"}}

1,6-Hexane diisothiocyanate

1,6-Hexane diisothiocyanate

{"author_name":"[email protected]","post_title":"1,6-Hexane diisothiocyanate","has_stock":{"has_stock_uk":"true","has_stock_germany":"false","has_stock_china":"false","has_stock_any":"true"},"sds_links":{"EN":"https:\/\/sds.fluorochem.co.uk\/eng\/sds_F008978_en.pdf","DA":"https:\/\/sds.fluorochem.co.uk\/dan\/sds_F008978_da.pdf","NL":"https:\/\/sds.fluorochem.co.uk\/nld\/sds_F008978_nl.pdf","FI":"https:\/\/sds.fluorochem.co.uk\/fin\/sds_F008978_fi.pdf","FR":"https:\/\/sds.fluorochem.co.uk\/fra\/sds_F008978_fr.pdf","DE":"https:\/\/sds.fluorochem.co.uk\/deu\/sds_F008978_de.pdf","IT":"https:\/\/sds.fluorochem.co.uk\/ita\/sds_F008978_it.pdf","NO":"https:\/\/sds.fluorochem.co.uk\/nor\/sds_F008978_no.pdf","PT":"https:\/\/sds.fluorochem.co.uk\/por\/sds_F008978_pt.pdf","ES":"https:\/\/sds.fluorochem.co.uk\/spa\/sds_F008978_es.pdf","SV":"https:\/\/sds.fluorochem.co.uk\/swe\/sds_F008978_sv.pdf"},"min_max_price":{"min_gbp_base_price":47,"max_gbp_base_price":198},"transport":[],"post_content":"CAS [5586-70-9]","hazards":{"signal_word":"Warning","hazard_statements":["H315 - Causes skin irritation.","H319 - Causes serious eye irritation.","H335 - May cause respiratory irritation."],"precautionary_phrases":["P261 - Avoid breathing dust\/fume\/gas\/mist\/vapours\/spray.","P264 - Wash hands thoroughly after handling.","P270 - Do not eat, drink or smoke when using this product.","P271 - Use only outdoors or in a well-ventilated area.","P280 - Wear protective gloves\/protective clothing and eye\/face protection.","P301+P312.1 - IF SWALLOWED: Call a doctor if you feel unwell.","P301+P330+P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.","P302+P352 - IF ON SKIN: Wash with plenty of water and soap.","P304+P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing.","P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.","P308+P313 - IF exposed or concerned: Get medical advice\/attention.","P321 - Specific treatment (see Section 4 on this SDS).","P362+P364 - Take off contaminated clothing and wash it before reuse.","P403+P233 - Store in a well-ventilated place. Keep container tightly closed.","P405 - Store locked up.","P501 - Dispose of contents\/container to hazardous waste disposal."],"ghs_pictograms":["GHS07"]},"variants_blob_url":"https:\/\/fluorochemcouk.blob.core.windows.net\/pricing\/F008978.json","post_name":"16-hexane-diisothiocyanate","post_date":"2025-03-21T11:28:03+00:00","meta":{"_cas":"5586-70-9","_canonicalsmiles":"S=C=NCCCCCCN=C=S","_inchi":"InChI=1S\/C8H12N2S2\/c11-7-9-5-3-1-2-4-6-10-8-12\/h1-6H2","_inchikey":"VZZPYUKWXDLMGI-UHFFFAOYSA-N","_mdl":"MFCD00041137","_molecularformula":"C8H12N2S2","_unspsc":12352100,"_sku":"F008978","_synonyms":[]},"shipping_times":{"UK":"UK Stock, Next Day, Germany Stock 3- 5 days, China Stock 10 - 14 days.","EU":"EU Stock, Next Day, UK Stock 3- 5 days, China Stock 10 - 14 days."},"post_type":"product","post_modified":"2025-06-25T08:51:04","ID":"771891","post_status":"publish","categories":{"concept_groups":["Isothiocyanate"],"term_id":[129]},"author_id":"1946","permalink":"https:\/\/fluorochem.build\/product\/F008978\/","properties":{"molecular_weight":"200.32","state":"Liquid","boiling_range":"183\u00b0C at 6 mmHg","appearance":"Liquid"}}

1,9-Decadiyne

{"author_name":"[email protected]","post_title":"1,9-Decadiyne","has_stock":{"has_stock_uk":"false","has_stock_germany":"false","has_stock_china":"true","has_stock_any":"true"},"sds_links":{"EN":"https:\/\/sds.fluorochem.co.uk\/eng\/sds_F009117_en.pdf","DA":"https:\/\/sds.fluorochem.co.uk\/dan\/sds_F009117_da.pdf","NL":"https:\/\/sds.fluorochem.co.uk\/nld\/sds_F009117_nl.pdf","FI":"https:\/\/sds.fluorochem.co.uk\/fin\/sds_F009117_fi.pdf","FR":"https:\/\/sds.fluorochem.co.uk\/fra\/sds_F009117_fr.pdf","DE":"https:\/\/sds.fluorochem.co.uk\/deu\/sds_F009117_de.pdf","IT":"https:\/\/sds.fluorochem.co.uk\/ita\/sds_F009117_it.pdf","NO":"https:\/\/sds.fluorochem.co.uk\/nor\/sds_F009117_no.pdf","PT":"https:\/\/sds.fluorochem.co.uk\/por\/sds_F009117_pt.pdf","ES":"https:\/\/sds.fluorochem.co.uk\/spa\/sds_F009117_es.pdf","SV":"https:\/\/sds.fluorochem.co.uk\/swe\/sds_F009117_sv.pdf"},"min_max_price":{"min_gbp_base_price":23,"max_gbp_base_price":420},"transport":[],"post_content":"CAS [1720-38-3]","hazards":{"signal_word":"Warning","hazard_statements":["H315 - Causes skin irritation.","H319 - Causes serious eye irritation.","H335 - May cause respiratory irritation."],"precautionary_phrases":["P261 - Avoid breathing dust\/fume\/gas\/mist\/vapours\/spray.","P264 - Wash hands thoroughly after handling.","P270 - Do not eat, drink or smoke when using this product.","P271 - Use only outdoors or in a well-ventilated area.","P280 - Wear protective gloves\/protective clothing and eye\/face protection.","P301+P312.1 - IF SWALLOWED: Call a doctor if you feel unwell.","P301+P330+P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.","P302+P352 - IF ON SKIN: Wash with plenty of water and soap.","P304+P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing.","P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.","P308+P313 - IF exposed or concerned: Get medical advice\/attention.","P321 - Specific treatment (see Section 4 on this SDS).","P362+P364 - Take off contaminated clothing and wash it before reuse.","P403+P233 - Store in a well-ventilated place. Keep container tightly closed.","P405 - Store locked up.","P501 - Dispose of contents\/container to hazardous waste disposal."],"ghs_pictograms":["GHS07"]},"variants_blob_url":"https:\/\/fluorochemcouk.blob.core.windows.net\/pricing\/F009117.json","post_name":"19-decadiyne","post_date":"2025-03-21T11:28:09+00:00","meta":{"_cas":"1720-38-3","_canonicalsmiles":"C#CCCCCCCC#C","_inchi":"InChI=1S\/C10H14\/c1-3-5-7-9-10-8-6-4-2\/h1-2H,5-10H2","_inchikey":"ILVDYAGPHFWNQI-UHFFFAOYSA-N","_mdl":"MFCD00014926","_molecularformula":"C10H14","_unspsc":12352100,"_sku":"F009117","_synonyms":[]},"shipping_times":{"UK":"UK Stock, Next Day, Germany Stock 3- 5 days, China Stock 10 - 14 days.","EU":"EU Stock, Next Day, UK Stock 3- 5 days, China Stock 10 - 14 days."},"post_type":"product","post_modified":"2025-06-25T08:51:04","ID":"772166","post_status":"publish","categories":{"concept_groups":["Alkyne","Terminal alkyne","Terminal alkyne (aliphatic hydrocarbon)"],"term_id":[120,129,93]},"author_id":"1946","permalink":"https:\/\/fluorochem.build\/product\/F009117\/","properties":{"purity":"99.0%","molecular_weight":"134.222","state":"Liquid","relative_density":"0.816","appearance":"Clear","odour":"Characteristic organic odour"}}

16-Bromo-1-hexadecanol

16-Bromo-1-hexadecanol

{"author_name":"[email protected]","post_title":"16-Bromo-1-hexadecanol","has_stock":{"has_stock_uk":"true","has_stock_germany":"true","has_stock_china":"true","has_stock_any":"true"},"sds_links":{"EN":"https:\/\/sds.fluorochem.co.uk\/eng\/sds_F011575_en.pdf","DA":"https:\/\/sds.fluorochem.co.uk\/dan\/sds_F011575_da.pdf","NL":"https:\/\/sds.fluorochem.co.uk\/nld\/sds_F011575_nl.pdf","FI":"https:\/\/sds.fluorochem.co.uk\/fin\/sds_F011575_fi.pdf","FR":"https:\/\/sds.fluorochem.co.uk\/fra\/sds_F011575_fr.pdf","DE":"https:\/\/sds.fluorochem.co.uk\/deu\/sds_F011575_de.pdf","IT":"https:\/\/sds.fluorochem.co.uk\/ita\/sds_F011575_it.pdf","NO":"https:\/\/sds.fluorochem.co.uk\/nor\/sds_F011575_no.pdf","PT":"https:\/\/sds.fluorochem.co.uk\/por\/sds_F011575_pt.pdf","ES":"https:\/\/sds.fluorochem.co.uk\/spa\/sds_F011575_es.pdf","SV":"https:\/\/sds.fluorochem.co.uk\/swe\/sds_F011575_sv.pdf"},"min_max_price":{"min_gbp_base_price":35,"max_gbp_base_price":1213},"transport":[],"post_content":"CAS [59101-28-9]","hazards":{"signal_word":"Warning","hazard_statements":["H315 - Causes skin irritation.","H319 - Causes serious eye irritation.","H335 - May cause respiratory irritation."],"precautionary_phrases":["P261 - Avoid breathing dust\/fume\/gas\/mist\/vapours\/spray.","P264 - Wash hands thoroughly after handling.","P270 - Do not eat, drink or smoke when using this product.","P271 - Use only outdoors or in a well-ventilated area.","P280 - Wear protective gloves\/protective clothing and eye\/face protection.","P301+P312.1 - IF SWALLOWED: Call a doctor if you feel unwell.","P301+P330+P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.","P302+P352 - IF ON SKIN: Wash with plenty of water and soap.","P304+P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing.","P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.","P308+P313 - IF exposed or concerned: Get medical advice\/attention.","P321 - Specific treatment (see Section 4 on this SDS).","P362+P364 - Take off contaminated clothing and wash it before reuse.","P403+P233 - Store in a well-ventilated place. Keep container tightly closed.","P405 - Store locked up.","P501 - Dispose of contents\/container to hazardous waste disposal."],"ghs_pictograms":["GHS07"]},"variants_blob_url":"https:\/\/fluorochemcouk.blob.core.windows.net\/pricing\/F011575.json","post_name":"16-bromo-1-hexadecanol","post_date":"2025-03-21T11:27:55+00:00","meta":{"_cas":"59101-28-9","_canonicalsmiles":"OCCCCCCCCCCCCCCCCBr","_inchi":"InChI=1S\/C16H33BrO\/c17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18\/h18H,1-16H2","_inchikey":"GOSQZSJMSMTIFI-UHFFFAOYSA-N","_mdl":"MFCD01076224","_molecularformula":"C16H33BrO","_unspsc":12352100,"_sku":"F011575","_synonyms":[]},"shipping_times":{"UK":"UK Stock, Next Day, Germany Stock 3- 5 days, China Stock 10 - 14 days.","EU":"EU Stock, Next Day, UK Stock 3- 5 days, China Stock 10 - 14 days."},"post_type":"product","post_modified":"2025-06-25T08:51:05","ID":"771535","post_status":"publish","categories":{"concept_groups":["Aliphatic alcohol","Brominated","Halogenated"],"term_id":[130,93]},"author_id":"1946","permalink":"https:\/\/fluorochem.build\/product\/F011575\/","properties":{"purity":"95.0%","molecular_weight":"321.343","state":"Solid","appearance":"Solid"}}

15-Bromo-1-pentadecanol

15-Bromo-1-pentadecanol

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14-Bromo-1-tetradecanol

14-Bromo-1-tetradecanol

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13-Bromo-1-tridecanol

13-Bromo-1-tridecanol

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Heterobifunctional crosslinkers – where the terminal groups have different reactivities – is often the most useful. It is much easier to precisely link this with that when you can differentiate them with orthogonal chemistry. When this is less of a concern, homobifunctional crosslinkers, with identical chemical groups at either end can be the most straightforward way to link molecules together.

Often the link between molecules needs to be permanent: however, in the case where the bioconjugation only needs to be temporary, numerous spacers that degrade under certain conditions have been developed. As release of payloads is the ultimate aim of antibody-drug conjugates (ADCs), many ADC linkers are cleavable.

In recent decades, photocleavable linkers have been used in a range of applications – allowing precise control of when and where a conjugate is released. Ortho-nitrobenzene derivatives allow clean photochemical cleavage when irradiated with near-UV light.

As a crosslinker or spacer can end up being a significant part of the accessible surface of a bioconjugate, its interaction with water can have a large impact on the behaviour of the overall molecule. If the conjugate requires specific properties to fulfil its purpose, it could impact its effectiveness.

Finding increasingly popularity as a hydrophilic and biocompatible crosslinker is polyethylene glycol: PEG are available in a range of lengths and modifiable with a range of chemistries at the termini. Ubiquitous crosslinkers, not just in the realm of bioconjugation, but also as polymer crosslinks for a range of biocompatible hydrogels.